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RNAi Induces Innate Immunity through Multiple Cellular Signaling Pathways

BACKGROUND & AIMS: Our previous results showed that the knockdown of woodchuck hepatitis virus (WHV) by RNA interference (RNAi) led to upregulation of interferon stimulated genes (ISGs) in primary hepatocytes. In the present study, we tested the hypothesis that the cellular signaling pathways re...

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Detalhes bibliográficos
Main Authors: Meng, Zhongji, Zhang, Xiaoyong, Wu, Jun, Pei, Rongjuan, Xu, Yang, Yang, Dongliang, Roggendorf, Michael, Lu, Mengji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659100/
https://ncbi.nlm.nih.gov/pubmed/23700487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064708
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