Age-of-onset-dependent influence of NOD2 gene variants on disease behaviour and treatment in Crohn’s disease

BACKGROUND: Influence of genetic variants in the NOD2 gene may play a more important role in disease activity, behaviour and treatment of pediatric- than adult-onset Crohn’s disease (CD). METHODS: 85 pediatric- and 117 adult-onset CD patients were tested for the three main NOD2 CD-associated variant...

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Autori principali: Posovszky, Carsten, Pfalzer, Veronika, Lahr, Georgia, Niess, Jan Hendrik, Klaus, Jochen, Mayer, Benjamin, Debatin, Klaus-Michael, von Boyen, Georg BT
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659055/
https://ncbi.nlm.nih.gov/pubmed/23635032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-77
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