Recombinant Rabies Viruses Expressing GM-CSF or Flagellin Are Effective Vaccines for Both Intramuscular and Oral Immunizations

Our previous studies indicated that recombinant rabies viruses (rRABV) expressing chemokines or cytokines (including GM-CSF) could enhance the immunogenicity by recruiting and/or activating dendritic cells (DC). In this study, bacterial flagellin was cloned into the RABV genome and recombinant virus...

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Detalhes bibliográficos
Main Authors: Zhou, Ming, Zhang, Guoqing, Ren, Guiping, Gnanadurai, Clement W., Li, Zhenguang, Chai, Qingqing, Yang, Yang, Leyson, Christina M., Wu, Wenxue, Cui, Min, Fu, Zhen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658976/
https://ncbi.nlm.nih.gov/pubmed/23700422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063384
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