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Sequence mutations of the substrate binding pocket of stem cell factor and multidrug resistance protein ABCG2 in renal cell cancer: A possible link to treatment resistance

ABCG2 is a multidrug cellular transport protein that is associated with resistance to certain treatments in patients, particularly anticancer treatment. The tumor-protective properties of ABCG2 expression are reported to be a feature of a subset of stem cell-like tumor cells. While protection agains...

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Detalhes bibliográficos
Main Authors: ZOERNIG, INKA, ZIEGELMEIER, CLAUDIA, LAHRMANN, BERND, GRABE, NIELS, JÄGER, DIRK, HALAMA, NIELS
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658860/
https://ncbi.nlm.nih.gov/pubmed/23467750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2324
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