Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma

BACKGROUND: Proteomic discovery of cancer biomarkers in body fluids is challenging because of their low abundance in a complex background. Altered gene expression in tumours may not reflect protein levels in body fluids. We have tested combining gene expression profiling of tumours with proteomic an...

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Dettagli Bibliografici
Autori principali: Shimwell, N J, Bryan, R T, Wei, W, James, N D, Cheng, K K, Zeegers, M P, Johnson, P J, Martin, A, Ward, D G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658509/
https://ncbi.nlm.nih.gov/pubmed/23591195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.157
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