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Role of Calcium Channels in Heavy Metal Toxicity

The role of voltage-dependent Ca channels (VDCC) in the membrane permeation of two toxic metals, lead (Pb) and cadmium (Cd), was studied in mammalian cells. Both metals interact with Ca-binding sites, but, while Cd influx appears to occur mainly through the same pathways as Ca, Pb is also rapidly ta...

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Bibliografiske detaljer
Hovedforfatter: Marchetti, Carla
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658387/
https://ncbi.nlm.nih.gov/pubmed/23724297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/184360
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