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TREM-2 Promotes Host Resistance Against Pseudomonas aeruginosa Infection by Suppressing Corneal Inflammation via a PI3K/Akt Signaling Pathway

PURPOSE. To explore the role of triggering receptor expressed on myeloid cells 2 (TREM-2) in Pseudomonas aeruginosa (PA) keratitis. METHODS. BALB/c mice were routinely infected with PA and evaluated at various postinfection time points for corneal expression of TREM-2, by real-time PCR, Western blot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Mingxia, Zhu, Min, Chen, Kang, Nie, Xinxin, Deng, Qiuchan, Hazlett, Linda D., Wu, Yongjian, Li, Meiyu, Wu, Minhao, Huang, Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658264/
https://ncbi.nlm.nih.gov/pubmed/23611998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10938
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