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Chromothripsis and Human Disease: Piecing Together the Shattering Process

The unprecedented resolution of high-throughput genomics has enabled the recent discovery of a phenomenon by which specific regions of the genome are shattered and then stitched together via a single devastating event, referred to as chromothripsis. Potential mechanisms governing this process are no...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maher, Christopher A., Wilson, Richard K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658123/
https://ncbi.nlm.nih.gov/pubmed/22265399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.006
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