A carregar...
Tetrathiomolybdate Inhibits Copper Trafficking Proteins Through Metal Cluster Formation
Tetrathiomolybdate (TM) is an orally active agent for treatment of disorders of copper metabolism. Here we describe how TM inhibits proteins that regulate copper physiology. Crystallographic results reveal that the surprising stability of the drug complex with the metallochaperone Atx1 arises from f...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658115/ https://ncbi.nlm.nih.gov/pubmed/19965379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1179907 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|