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Gene Transfer of Apolipoprotein A-V Improves the Hypertriglyceridemic Phenotype of apoa5 (−/−) Mice

OBJECTIVE: Apolipoprotein (apo) A-V is a low abundance protein with a profound influence on plasma triacylglycerol levels. In human populations, single nucleotide polymorphisms and mutations in APOA5 positively correlate with hypertriglyceridemia. As an approach to preventing the deleterious effects...

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Huvudupphovsmän: Sharma, Vineeta, Beckstead, Jennifer A., Simonsen, Jens B., Nelbach, Lisa, Watson, Gordon, Forte, Trudy M., Ryan, Robert O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658105/
https://ncbi.nlm.nih.gov/pubmed/23329134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301078
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