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Stability of temozolomide in solutions aimed for oral treatment prepared from a commercially available powder for infusion

BACKGROUND: Temozolomide (TMZ) is an alkylating agent with a broad spectrum of antitumor activity, including brain tumors in children. The oral use of TMZ is hampered by the lack of a suitable galenic formulation, since the capsules of TMZ (Temodal™) are large and difficult to swallow. A powder for...

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Detalhes bibliográficos
Main Authors: Nygren, Helen, Eksborg, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658070/
https://ncbi.nlm.nih.gov/pubmed/23781469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2229-4708.97700
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