Differential hERG ion channel activity of ultrasmall gold nanoparticles

Understanding the mechanism of toxicity of nanomaterials remains a challenge with respect to both mechanisms involved and product regulation. Here we show toxicity of ultrasmall gold nanoparticles (AuNPs). Depending on the ligand chemistry, 1.4-nm-diameter AuNPs failed electrophysiology-based safety...

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Autors principals: Leifert, Annika, Pan, Yu, Kinkeldey, Anne, Schiefer, Frank, Setzler, Julia, Scheel, Olaf, Lichtenbeld, Hera, Schmid, Günter, Wenzel, Wolfgang, Jahnen-Dechent, Willi, Simon, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Physical Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657833/
https://ncbi.nlm.nih.gov/pubmed/23630249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220143110
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