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Levetiracetam has no acute effects on brain γ-aminobutyric acid levels

OBJECTIVE: The mechanism of action of levetiracetam (LEV), an antiepileptic drug, is related to a novel binding site, SV2, but LEV acts on GABA-A receptors. The objective of the study described here was to determine if LEV modulates brain GABA in vivo. METHODS: Concentrations of cerebral GABA and se...

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Bibliografiske detaljer
Main Authors: Kuzniecky, R., Pan, J., Burns, A., Devinsky, O., Hetherington, H.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657745/
https://ncbi.nlm.nih.gov/pubmed/18286712
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