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P2X(7) receptors control 2-arachidonoylglycerol production by microglial cells

Endogenous cannabinoid ligands (endocannabinoids) produced by neurons, astrocytes, and microglial cells activate cannabinoid receptors, the molecular target for marijuana's bioactive ingredient Δ(9)-tetrahydrocannabinol. The molecular mechanism underlying the production of the most abundant end...

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Detalhes bibliográficos
Main Authors: Witting, Anke, Walter, Lisa, Wacker, Jennifer, Möller, Thomas, Stella, Nephi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365769/
https://ncbi.nlm.nih.gov/pubmed/14976257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306707101
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