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EFFECTS OF METHYLNALTREXONE ON GUINEA PIG GASTROINTESTINAL MOTILITY

The purpose of the present study was to compare the effects of methylnaltrexone (MNTX), a peripherally acting μ opioid receptor (μOR) antagonist, on gastrointestinal (GI) motility in naïve vs. opiate-chronically treated guinea pigs in vitro and in vivo. We have used the electrically stimulated muscl...

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Autors principals: Anselmi, Laura, Huynh, Jennifer, Vegezzi, Gaia, Sternini, Catia
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657610/
https://ncbi.nlm.nih.gov/pubmed/23361094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-013-0833-8
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