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MRI analysis of cerebellar and vestibular developmental phenotypes in Gbx2 conditional knockout mice

PURPOSE: Our aim in this study was to apply three-dimensional (3D) MRI methods to analyze early postnatal morphological phenotypes in a Gbx2 conditional knockout (Gbx2-CKO) mouse that has variable midline deletions in the central cerebellum, reminiscent of many human cerebellar hypoplasia syndromes....

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Detalhes bibliográficos
Main Authors: Szulc, Kamila U., Nieman, Brian J., Houston, Edward J., Bartelle, Benjamin B., Lerch, Jason P., Joyner, Alexandra L., Turnbull, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657598/
https://ncbi.nlm.nih.gov/pubmed/23400959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24597
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