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Innate immunity in the Grid2(Lc/+) mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

BACKGROUND: There is growing evidence that the death receptor CD95 has a wider role in non-apoptotic functions. In the brain, it may contribute to neural death and to the associated inflammatory reaction via a non-apoptotic pathway. Brain injury triggers an inflammatory reaction in which the CD95/CD...

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Detalhes bibliográficos
Main Authors: Vernet-der Garabedian, Béatrice, Derer, Paul, Bailly, Yannick, Mariani, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657541/
https://ncbi.nlm.nih.gov/pubmed/23672668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-65
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