Effect of Lutein and Antioxidant Supplementation on VEGF Expression, MMP-2 Activity, and Ultrastructural Alterations in Apolipoprotein E-Deficient Mouse

Oxidative stress is involved in the pathogenesis of several diseases such as atherosclerosis and age-related macular degeneration (AMD). ApoE-deficient mice (apoE(−/−)) are a well-established model of genetic hypercholesterolemia and develop retinal alterations similar to those found in humans with...

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Detalhes bibliográficos
Main Authors: Fernández-Robredo, Patricia, Sádaba, Luis M., Salinas-Alamán, Angel, Recalde, Sergio, Rodríguez, José A., García-Layana, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657460/
https://ncbi.nlm.nih.gov/pubmed/23738034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/213505
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