Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum

Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin h...

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Detalhes bibliográficos
Main Authors: Puddu, Alessandra, Sanguineti, Roberta, Durante, Arianna, Nencioni, Alessio, Mach, François, Montecucco, Fabrizio, Viviani, Giorgio L.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657444/
https://ncbi.nlm.nih.gov/pubmed/23737644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/317120
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