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The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only β cell-specific activator. Here, we show that MafA selectively induces endogenous insulin transcription in non-β cells. MafA was also first detected in the insulin-producing cells formed d...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365722/ https://ncbi.nlm.nih.gov/pubmed/14973194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306233101 |
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