The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only β cell-specific activator. Here, we show that MafA selectively induces endogenous insulin transcription in non-β cells. MafA was also first detected in the insulin-producing cells formed d...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14973194/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306233101 |
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