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A role for NT-3 in the hyperinnervation of neonatally wounded skin

Neurotrophin-3 (NT-3) is a target-derived neurotrophic factor that regulates sensory neuronal survival and growth. Here we report that NT-3 plays a critical permissive role in cutaneous sensory nerve sprouting that contributes to pain and sensitivity following skin wounding in young animals. Sensory...

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Detalhes bibliográficos
Main Authors: Beggs, Simon, Alvares, Debie, Moss, Andrew, Currie, Gillian, Middleton, Jacqueta, Salter, Michael W., Fitzgerald, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657181/
https://ncbi.nlm.nih.gov/pubmed/22871470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.07.012
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