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Two discriminatory binding sites in the Escherichia coli replication origin are required for DNA strand opening by initiator DnaA-ATP

Initiation of DNA replication in eukaryotes, archea, and eubacteria requires interaction of structurally conserved ATP-binding initiator proteins and origin DNA to mediate assembly of replisomes. However, the specific requirement for ATP in the early steps of initiation remains unclear. This is true...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: McGarry, Kevin C., Ryan, Valorie T., Grimwade, Julia E., Leonard, Alan C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365702/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400340101
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