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Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid

Twenty-eight amino acid residues involved in most noncovalent interactions between trimeric protein subunits in the capsid of the parvovirus minute virus of mice were truncated individually to alanine, and the effects on capsid assembly, thermostability, and conformation were analyzed. Only seven si...

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Détails bibliographiques
Auteurs principaux: Reguera, Juan, Carreira, Aura, Riolobos, Laura, Almendral, José María, Mateu, Mauricio G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC365688/
https://ncbi.nlm.nih.gov/pubmed/14981262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307748101
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