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Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid

Twenty-eight amino acid residues involved in most noncovalent interactions between trimeric protein subunits in the capsid of the parvovirus minute virus of mice were truncated individually to alanine, and the effects on capsid assembly, thermostability, and conformation were analyzed. Only seven si...

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Detalhes bibliográficos
Main Authors: Reguera, Juan, Carreira, Aura, Riolobos, Laura, Almendral, José María, Mateu, Mauricio G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365688/
https://ncbi.nlm.nih.gov/pubmed/14981262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307748101
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