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Clan Genomics and the Complex Architecture of Human Disease

Human diseases are caused by alleles that encompass the full range of variant types, from single-nucleotide changes to copy-number variants, and these variations span a broad frequency spectrum, from the very rare to the common. The picture emerging from analysis of whole-genome sequences, the 1000...

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Detalhes bibliográficos
Main Authors: Lupski, James R., Belmont, John W., Boerwinkle, Eric, Gibbs, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656718/
https://ncbi.nlm.nih.gov/pubmed/21962505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.008
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