Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation

Pulmonary TNFα has been linked to reduced exercise capacity in a subset of patients with moderate to severe chronic obstructive pulmonary disease (COPD). We hypothesized that prolonged, high expression of pulmonary TNFα impairs cardiac and skeletal muscle function, and both contribute to exercise li...

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Main Authors: Tang, Kechun, Murano, George, Wagner, Harrieth, Nogueira, Leonardo, Wagner, Peter D., Tang, Alisa, Dalton, Nancy D., Gu, Yusu, Peterson, Kirk L., Breen, Ellen C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656431/
https://ncbi.nlm.nih.gov/pubmed/23449936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00607.2012
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