Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

Allogeneic natural killer (NK) cells are used for adoptive immunotherapy after stem cell transplantation. In order to overcome technical limitations in NK cell purification and activation, the following study investigates the impact of different variables on NK cell recovery, cytotoxicity, and T-cel...

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Detalhes bibliográficos
Main Authors: Koehl, Ulrike, Brehm, Claudia, Huenecke, Sabine, Zimmermann, Stefanie-Yvonne, Kloess, Stephan, Bremm, Melanie, Ullrich, Evelyn, Soerensen, Jan, Quaiser, Andrea, Erben, Stephanie, Wunram, Claudia, Gardlowski, Tanja, Auth, Eileen, Tonn, Torsten, Seidl, Christian, Meyer-Monard, Sandrine, Stern, Martin, Passweg, Jakob, Klingebiel, Thomas, Bader, Peter, Schwabe, Dirk, Esser, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656406/
https://ncbi.nlm.nih.gov/pubmed/23730623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00118
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