Clinical Grade Purification and Expansion of NK Cell Products for an Optimized Manufacturing Protocol

Allogeneic natural killer (NK) cells are used for adoptive immunotherapy after stem cell transplantation. In order to overcome technical limitations in NK cell purification and activation, the following study investigates the impact of different variables on NK cell recovery, cytotoxicity, and T-cel...

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Hauptverfasser: Koehl, Ulrike, Brehm, Claudia, Huenecke, Sabine, Zimmermann, Stefanie-Yvonne, Kloess, Stephan, Bremm, Melanie, Ullrich, Evelyn, Soerensen, Jan, Quaiser, Andrea, Erben, Stephanie, Wunram, Claudia, Gardlowski, Tanja, Auth, Eileen, Tonn, Torsten, Seidl, Christian, Meyer-Monard, Sandrine, Stern, Martin, Passweg, Jakob, Klingebiel, Thomas, Bader, Peter, Schwabe, Dirk, Esser, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656406/
https://ncbi.nlm.nih.gov/pubmed/23730623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00118
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