Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder

Genome-wide association studies (GWAS) have implicated ANK3 as a susceptibility gene for bipolar disorder (BP). We examined whether epistasis with ANK3 may contribute to the “missing heritability” in BP. We first identified via the STRING database 14 genes encoding proteins with prior biological evi...

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Detalhes bibliográficos
Main Authors: Judy, Jennifer Toolan, Seifuddin, Fayaz, Pirooznia, Mehdi, Mahon, Pamela Belmonte, Jancic, Dubravka, Goes, Fernando S., Schulze, Thomas, Cichon, Sven, Noethen, Markus, Rietschel, Marcella, DePaulo, J. Raymond, Potash, James B., Zandi, Peter P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656345/
https://ncbi.nlm.nih.gov/pubmed/23730306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00087
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