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Inhibition of HIV-1 Transcription and Replication by a Newly Identified Cyclin T1 Splice Variant
A variety of cellular factors participates in the HIV-1 life cycle. Among them is the well characterized cyclin T1 (CYCT1). CycT1 binds to cyclin-dependent kinase 9 (CDK9) and forms the positive transcription elongation factor-b (P-TEFb). P-TEFb is then recruited by HIV-1 TAT to the HIV-1 long termi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656286/ https://ncbi.nlm.nih.gov/pubmed/23569210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438465 |
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