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Neurogentics of Dopaminergic Receptor Super-sensitivity in Activation of Brain Reward Circuitry and Relapse: Proposing “Deprivation-Amplification Relapse Therapy” (DART)

BACKGROUND AND HYPOTHESIS: It is well known that after prolonged abstinence, individuals who imbibe or use their drug of choice experience a powerful euphoria that precipitates serious relapse. While a biological explanation for this conundrum has remained elusive, we hypothesize that this clinicall...

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Bibliographische Detailangaben
Hauptverfasser: Blum, Kenneth, Chen, Thomas J.H., Downs, B. William, Bowirrat, Abdalla, Waite, Roger L., Braverman, Eric R., Madigan, Margaret, Oscar-Berman, Marlene, DiNubile, Nicholas, Gold, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656125/
https://ncbi.nlm.nih.gov/pubmed/19940429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3810/pgm.2009.11.2087
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