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Quantifying the Molecular Origins of Opposite Solvent Effects on Protein-Protein Interactions

Although the nature of solvent-protein interactions is generally weak and non-specific, addition of cosolvents such as denaturants and osmolytes strengthens protein-protein interactions for some proteins, whereas it weakens protein-protein interactions for others. This is exemplified by the puzzling...

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Detalhes bibliográficos
Main Authors: Vagenende, Vincent, Han, Alvin X., Pek, Han B., Loo, Bernard L. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656110/
https://ncbi.nlm.nih.gov/pubmed/23696727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003072
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