Protective efficacy of a recombinant BCG secreting antigen 85B/Rv3425 fusion protein against Mycobacterium tuberculosis infection in mice

In this study, the protective efficacy of a novel recombinant BCG strain co-expressing Ag85B and Rv3425 against Mycobacterium tuberculosis H37Rv was evaluated in mice. This rBCG::Ag85B-Rv3425 strain could provide similar or even better protective efficacy against M. tuberculosis challenge compared w...

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Bibliographic Details
Main Authors: Wang, Jiuling, Qie, Yaqing, Liu, Wei, Wang, Honghai
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656079/
https://ncbi.nlm.nih.gov/pubmed/22906934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.21817
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