Recombinant Mycobacterium bovis BCG Expressing the Chimeric Protein of Antigen 85B and ESAT-6 Enhances the Th1 Cell-Mediated Response

The chimeric protein that relies on the T-cell epitopes of antigen 85B (Ag85B) and the 6-kDa early secreted antigen target (ESAT-6) has been demonstrated to augment the Th1 immune response. In this study, we developed a recombinant Mycobacterium bovis BCG (rBCG) strain that secretes the chimeric pro...

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Detalhes bibliográficos
Main Authors: Xu, Ying, Liu, Wei, Shen, Hongbo, Yan, Jingran, Qu, Di, Wang, Honghai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Immune Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725546/
https://ncbi.nlm.nih.gov/pubmed/19515867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00112-09
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