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Mitochondrial calcium uniporter, MiRNA and cancer: Live and let die

Mitochondria receive calcium (Ca(2+)) signals from endoplasmic reticulum (ER) and decode them into pro-apoptotic inputs, which lead to cell death. Therefore, mitochondrial Ca(2+) overload is considered a fundamental trigger of the apoptotic process, and several oncogenes and tumor suppressors modify...

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Autors principals: Marchi, Saverio, Pinton, Paolo
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656015/
https://ncbi.nlm.nih.gov/pubmed/23713134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.23818
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