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A silencer element from the alpha-globin gene inhibits expression of beta-like genes.

We have studied the cis and trans interactions of the alpha- and beta-globin genes in a transient expression system. We found that the alpha-globin gene inhibited beta-globin expression in cis but not in trans. The silencer element responsible for this inhibition was localized to a 259-base-pair fra...

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Bibliografiske detaljer
Main Authors: Atweh, G F, Liu, J M, Brickner, H E, Zhu, X X
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC365600/
https://ncbi.nlm.nih.gov/pubmed/2850473
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