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Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors

BACKGROUND: Metabolic abnormalities are common in HIV-infected individuals on antiretroviral therapy (ART), but the biochemical details and underlying mechanisms of these disorders have not been defined. METHODS: Untargeted metabolomic profiling of plasma was performed for 32 HIV patients with low n...

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Detalhes bibliográficos
Main Authors: Cassol, Edana, Misra, Vikas, Holman, Alexander, Kamat, Anupa, Morgello, Susan, Gabuzda, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655873/
https://ncbi.nlm.nih.gov/pubmed/23641933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-203
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