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Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa
BACKGROUND: Cytochrome P450 3A5 (CYP3A5) is an enzyme involved in the metabolism of many therapeutic drugs. CYP3A5 expression levels vary between individuals and populations, and this contributes to adverse clinical outcomes. Variable expression is largely attributed to four alleles, CYP3A5*1 (expre...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655848/ https://ncbi.nlm.nih.gov/pubmed/23641907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-34 |
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