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Rac GEF Dock4 interacts with cortactin to regulate dendritic spine formation

In neuronal development, dendritic spine formation is important for the establishment of excitatory synaptic connectivity and functional neural circuits. Developmental deficiency in spine formation results in multiple neuropsychiatric disorders. Dock4, a guanine nucleotide exchange factor (GEF) for...

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Autores principales: Ueda, Shuhei, Negishi, Manabu, Katoh, Hironori
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655820/
https://ncbi.nlm.nih.gov/pubmed/23536706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-11-0782
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