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Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression.

X8/6T2, a hamster-human hybrid cell line which contains an inactive human X chromosome, was treated with 5-azacytidine and selected for derepression of hypoxanthine-guanine phosphoribosyltransferase. Clones were examined for coreactivation of the phosphoglycerate kinase gene (Pgk). Of 68 of these hy...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Hansen, R S, Ellis, N A, Gartler, S M
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1988
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2850467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.11.4692-4699.1988
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