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Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain

The FIC motif and the eukaryotic-like ankyrin repeats are found in many bacterial type IV effectors, yet little is known about how these domains enable bacteria to modulate host cell functions. Bacterial FIC domains typically bind ATP and transfer adenosine monophosphate moiety onto target proteins....

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Detalhes bibliográficos
Main Authors: Campanacci, Valérie, Mukherjee, Shaeri, Roy, Craig R, Cherfils, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655470/
https://ncbi.nlm.nih.gov/pubmed/23572077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.82
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