Physiologically Based Toxicokinetics of Serum Aflatoxin B(1)-Lysine Adduct in F344 Rats

Aflatoxin B(1)-lysine adduct (AFB-Lys) is a reliable biomarker for aflatoxin exposure; however, a systematic toxicokinetic evaluation has not been reported. In this study, male F344 rats were orally exposed to single, or repeated, doses of AFB(1) and the toxicokinetics of serum AFB-Lys that followed...

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Main Authors: Qian, Guoqing, Tang, Lili, Wang, Franklin, Guo, Xia, Massey, Michael E., Williams, Jonathan H., Phillips, Timothy D., Wang, Jia-Sheng
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655440/
https://ncbi.nlm.nih.gov/pubmed/23146766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.10.020
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