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Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene.

The human alpha-1-antitrypsin (AAT) gene is expressed in the liver, and its deficiency causes pulmonary emphysema. We have demonstrated that its 5'-flanking region contains cis-acting elements capable of directing proper transcription in the presence of rat liver nuclear extract. The in vitro t...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Li, Y, Shen, R F, Tsai, S Y, Woo, S L
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1988
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3263567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4362
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