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Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures

BACKGROUND: Germ cell development involves formation of the spermatogenic or oogenic lineages from the bipotential primordial germ cells. Signaling mechanisms in the fetal testis and ovary determine whether germ cells enter the male or female developmental pathway, respectively. These signaling proc...

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Main Authors: Wakeling, Stephanie I, Miles, Denise C, Western, Patrick S
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655070/
https://ncbi.nlm.nih.gov/pubmed/23631647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-168
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