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Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures

BACKGROUND: Germ cell development involves formation of the spermatogenic or oogenic lineages from the bipotential primordial germ cells. Signaling mechanisms in the fetal testis and ovary determine whether germ cells enter the male or female developmental pathway, respectively. These signaling proc...

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書誌詳細
主要な著者: Wakeling, Stephanie I, Miles, Denise C, Western, Patrick S
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655070/
https://ncbi.nlm.nih.gov/pubmed/23631647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-168
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