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Fermitins, the Orthologs of Mammalian Kindlins, Regulate the Development of a Functional Cardiac Syncytium in Drosophila melanogaster

The vertebrate Kindlins are an evolutionarily conserved family of proteins critical for integrin signalling and cell adhesion. Kindlin-2 (KIND2) is associated with intercalated discs in mice, suggesting a role in cardiac syncytium development; however, deficiency of Kind2 leads to embryonic lethalit...

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Bibliografische gegevens
Hoofdauteurs: Catterson, James H., Heck, Margarete M. S., Hartley, Paul S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655056/
https://ncbi.nlm.nih.gov/pubmed/23690969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062958
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