Long-term renal changes in the liver-specific glucokinase knockout mouse: implications for renal disease in MODY2

To investigate the functional and structural renal changes in a long-term liver-specific glucokinase knockout mouse, model of MODY2. Hemizygous glucokinase knockout mice, gck(w/−) groups, were compared at 6-, 10- and 14-months to their age-matched normal littermates, gck(w/w) groups. To examine chan...

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Главные авторы: Gu, Yi, Mao, Yiqing, Li, Hui, Zhao, Shuyong, Yang, Yang, Gao, Hui, Yu, Jianqiang, Zhang, Xuemei, Irwin, David M., Tan, Huanran
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654931/
https://ncbi.nlm.nih.gov/pubmed/21316027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2010.11.003
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