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BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge

BACKGROUND: With the recent decreasing cost of genome sequence data, there has been increasing interest in rare variants and methods to detect their association to disease. We developed BioBin, a flexible collapsing method inspired by biological knowledge that can be used to automate the binning of...

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Detalhes bibliográficos
Main Authors: Moore, Carrie B, Wallace, John R, Frase, Alex T, Pendergrass, Sarah A, Ritchie, Marylyn D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654874/
https://ncbi.nlm.nih.gov/pubmed/23819467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-S2-S6
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