Analysis of small-sample clinical genomics studies using multi-parameter shrinkage: application to high-throughput RNA interference screening

High-throughput (HT) RNA interference (RNAi) screens are increasingly used for reverse genetics and drug discovery. These experiments are laborious and costly, hence sample sizes are often very small. Powerful statistical techniques to detect siRNAs that potentially enhance treatment are currently l...

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Detalhes bibliográficos
Main Authors: van de Wiel, Mark A, de Menezes, Renée X, Siebring-van Olst, Ellen, van Beusechem, Victor W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654870/
https://ncbi.nlm.nih.gov/pubmed/23819807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-S2-S1
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