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Genome scan in familial late-onset Alzheimer’s disease: a locus on chromosome 6 contributes to age at onset

Alzheimer’s disease (AD) is a common, genetically complex, fatal neurodegenerative disorder of late life. Although several genes are known to play a role in early-onset AD, identification of the genetic basis of late onset AD (LOAD) has been challenging, with only the APOE gene known to have a high...

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Detalhes bibliográficos
Main Authors: Zhao, Wei, Marchani, Elizabeth E., Cheung, Charles Y. K., Steinbart, Ellen J., Schellenberg, Gerard D., Bird, Thomas D., Wijsman, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654841/
https://ncbi.nlm.nih.gov/pubmed/23355194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32133
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