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Osteoblasts Are a Major Source of Inflammatory Cytokines in the Tumor Microenvironment of Bone Metastatic Breast Cancer

Metastatic breast cancer cells co-opt the cells of the bone to increase their production of inflammatory cytokines. Here, we sought to identify key cytokines expressed by osteoblasts in vitro and in vivo in the presence of MDA-MB-231 metastatic breast cancer cells, including a bone-seeking variant....

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Detalhes bibliográficos
Main Authors: Bussard, Karen M., Venzon, David J., Mastro, Andrea M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654838/
https://ncbi.nlm.nih.gov/pubmed/20683902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22799
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